Lain—driven by the abrupt suicide of a classmate—logs on to the Wired and promptly loses herself in a twisted mass of hallucinations, memories, and interconnected-psyches.
| Writing | Chiaki J. Konaka | Screenplay |
| Writing | Chiaki J. Konaka | Series Composition |
| Writing | Yasuyuki Ueda | Original Series Creator |
| Writing | Yasuyuki Ueda | Original Story |
| Sound | Reichi Nakaido | Original Music Composer |
| Sound | Alex Caird | Theme Song Performance |
| Sound | Jasmine Rodgers | Main Title Theme Composer |
| Sound | Jasmine Rodgers | Theme Song Performance |
| Sound | Lee Sullivan | Theme Song Performance |
| Sound | Ben Henderson | Theme Song Performance |
| Sound | Paul Turrell | Theme Song Performance |
| Sound | Steve Rodgers | Theme Song Performance |
| Visual Effects | Tokuyuki Matsutake | Opening/Ending Animation |
| Visual Effects | Akihiko Yamashita | Opening/Ending Animation |
| Visual Effects | Hidenori Matsubara | Opening/Ending Animation |
| Visual Effects | Hirofumi Suzuki | Opening/Ending Animation |
| Visual Effects | Toshiyuki Tsuru | Opening/Ending Animation |
| Visual Effects | Tomokazu Tokoro | Opening/Ending Animation |
| Visual Effects | Kouichi Arai | Opening/Ending Animation |
| Visual Effects | Yoshitoshi ABe | Visual Effects |
| Visual Effects | Yoshitoshi ABe | Character Designer |
| Camera | Takashi Azuhata | Director of Photography |
| Production | Yasuyuki Ueda | Producer |
| Editing | Tsuyoshi Imai | Editor |
| Art | Masaru Sato | Art Direction |
| Production | Taro Maki | Producer |
