The modern-day vampire comedy centers on high school girl Amano, who was saved from a strange incident by a vampire girl named Sophie Twilight, and has been interested in her ever since. Akari arrives at her house uninvited and the two start to live together. Although a vampire, Sophie never attacks humans, but purchases blood and anime goods via mail and lives a modern life.
You can now watch Ms. Vampire Who Lives in My Neighborhood. online on the following streaming providers in the United States.
| Writing | Tatsuya Takahashi | Series Composition |
| Directing | Noriaki Akitaya | Series Director |
| Visual Effects | Yoko Suzuki | Color Designer |
| Production | Yuichi Izumi | Producer |
