The exploits of FBI Special Agents Fox Mulder and Dana Scully who investigate X-Files: marginalized, unsolved cases involving paranormal phenomena. Mulder believes in the existence of aliens and the paranormal while Scully, a skeptic, is assigned to make scientific analyses of Mulder's discoveries that debunk Mulder's work and thus return him to mainstream cases.
After being duped and going bankrupt, model Maddie is convinced by David to become a partner in a detective agency. Together they solve various cases, while getting comfortable with each other.