In a world shaken by an epidemic of madness that spreads through speech, Murat is the only immune person. As he searches for the secret of his mysterious immunity, his “hot skull", he has to leave the safe zone and embark on an adventure within the ruins of Istanbul.
Gil Oh-so, an employee at a cleaning company, meets Jang Seon-gyul, the boss of the company. The two are diametric opposite when it comes to cleanliness. With the help of Oh-sol, Seon-gyul faces his mysophobia and falls in love with her.
Bennie Upshaw, the head of a Black working class family in Indianapolis, is a charming, well-intentioned mechanic and lifelong mess just trying his best to step up and care for his family and tolerate his sardonic sister-in-law, all without a blueprint for success.
As Si Tu Mo's graduation is nearing, she is confused about her future plans. Her ordinary days are suddenly shaken up when the genius Physics student Gu Wei Yi appears in her life. The two accidentally end up living together and chaos begins.
After the death of her husband, a grieving widow and a tormented ex-cop investigate a series of murders apparently related to the Universal Expo held in Seville in 1992.