Young Jeremiah lives in a stable environment with loving foster parents until the day his troubled mother, Sarah, returns to claim him. Jeremiah becomes swept up in his mother's dangerous world of drugs, seedy hotels, strip joints and revolving lovers. Salvation comes in the form of the boy's ultrareligious grandparents, but soon Jeremiah's mother returns. Maternal love binds the pair together on the road until Sarah's desperate and depraved lifestyle finally consumes her.
Unfortunately the movie The Heart Is Deceitful Above All Things is not yet available on HBO Max.
| Writing | Asia Argento | Screenplay |
| Writing | Alessandro Magania | Writer |
| Sound | Kim Gordon | Music |
| Production | Shannon Makhanian | Casting |
| Sound | Morgan | Music |
| Art | Max Biscoe | Production Design |
| Art | Anuradha Mehta | Set Decoration |
| Costume & Make-Up | Mel Ottenberg | Costume Design |
| Editing | Jim Mol | Editor |
| Sound | Billy Corgan | Music |
| Camera | Eric Alan Edwards | Director of Photography |
| Writing | Laura Albert | Author |
| Production | Alain de la Mata | Producer |
| Production | Chris Hanley | Producer |
| Costume & Make-Up | Fleur Morell | Key Makeup Artist |
| Costume & Make-Up | Mel Ottenberg | Hairstylist |
| Production | Lawrence E. Davis | Producer |
| Costume & Make-Up | Mike Potter | Makeup Artist |
| Production | David Hillary | Producer |
| Directing | Asia Argento | Director |
| Production | Roberta Hanley | Producer |
| Directing | Jennifer Fiedler | First Assistant Director |
