Columbo is a friendly, verbose, disheveled-looking police detective who is consistently underestimated by his suspects. Despite his unprepossessing appearance and apparent absentmindedness, he shrewdly solves all of his cases and secures all evidence needed for indictment. His formidable eye for detail and meticulously dedicated approach often become clear to the killer only late in the storyline.
After discovering that his late father has gone through most of the family fortune, Tod Stiles hits the title trans-America highway in his Corvette in search of adventure with friend Buz Murdock, a survivor of New York's mean streets. The two work odd jobs as they meet and interact with colorful characters and find themselves plunged into one situation after another, some of them romantic, some of them very dangerous. Later, Linc Case, a Vietnam war hero trying to find himself, takes over as Tod's travel companion.
Diagnosis: Unknown is an American medical drama that aired on CBS from July 5 to September 20, 1960. Produced by Bob Banner, the series aired as a summer replacement for The Garry Moore Show, a variety program.