Popular Comedy TV Series on Amazon Prime Video

House

2004

House

2004
8.6
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.
Slow Horses

2022

Slow Horses

2022
8
Follow a dysfunctional team of MI5 agents—and their obnoxious boss, the notorious Jackson Lamb—as they navigate the espionage world's smoke and mirrors to defend England from sinister forces.
Teen Wolf

2011

Teen Wolf

2011
8.5
Scott McCall, a high school student living in the town of Beacon Hills has his life drastically changed when he's bitten by a werewolf, becoming one himself. He must henceforth learn to balance his problematic new identity with his day-to-day teenage life. The following characters are instrumental to his struggle: Stiles, his best friend; Allison, his love interest who comes from a family of werewolf hunters; and Derek, a mysterious werewolf with a dark past. Throughout the series, he strives to keep his loved ones safe while maintaining normal relationships with them.
Desperate Housewives

2004

Desperate Housewives

2004
7.9
Looking down on her friends and family isn't a way of life for Mary Alice Young... it's a way of death. One day, in her perfect house, in the loveliest of suburbs, Mary Alice ended it all. Now she's taking us into the lives of her family, friends and neighbors, commenting from her elevated P.O.V.
Charmed

1998

Charmed

1998
8.2
Three sisters (Prue, Piper and Phoebe) reunite and unlock their powers to become the Charmed Ones, the most powerful good witches of all time, whose prophesied destiny is to protect innocent lives from evil beings such as demons and warlocks. Each sister possesses unique magical powers that grow and evolve, while they attempt to maintain normal lives in modern day San Francisco.
Frasier

1993

Frasier

1993
7.7
After many years spent at the “Cheers” bar, Frasier moves back home to Seattle to work as a radio psychiatrist after his policeman father gets shot in the hip on duty.
Monk

2002

Monk

2002
8
Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.
Psych

2006

Psych

2006
7.9
Thanks to his police officer father's efforts, Shawn Spencer spent his childhood developing a keen eye for detail (and a lasting dislike of his dad). Years later, Shawn's frequent tips to the police lead to him being falsely accused of a crime he solved. Now, Shawn has no choice but to use his abilities to perpetuate his cover story: psychic crime-solving powers, all the while dragging his best friend, his dad, and the police along for the ride.
Hazbin Hotel

2024

Hazbin Hotel

2024
8.7
In attempt to find a non-violent alternative for reducing Hell's overpopulation, the daughter of Lucifer opens a rehabilitation hotel that offers a group of misfit demons a chance at redemption.
The Nanny

1993

The Nanny

1993
8.1
Fran, fresh out of her job as a bridal consultant in her boyfriend’s shop, first appears on the doorstep of Broadway producer Maxwell Sheffield peddling cosmetics, and quickly stumbled upon the opportunity to become The Nanny for his three children. But soon Fran, with her offbeat nurturing and no-nonsense honesty, touches Maxwell as well as the kids.
The Middle

2009

The Middle

2009
7.6
The daily mishaps of a married woman and her semi-dysfunctional family and their attempts to survive life in general in the city of Orson, Indiana.
Confidence Queen

2025

Confidence Queen

2025
7.7
Three con artists with different backgrounds, team up for a daring and adventurous scheme of revenge against the villains of this era.
The Andy Griffith Show

1960

The Andy Griffith Show

1960
7.6
The Andy Griffith Show is an American sitcom first televised on CBS between October 3, 1960 and April 1, 1968. Andy Griffith portrays the widowed sheriff of the fictional small community of Mayberry, North Carolina. His life is complicated by an inept, but well-meaning deputy, Barney Fife, a spinster aunt and housekeeper, Aunt Bee, and a precocious young son, Opie. Local ne'er-do-wells, bumbling pals, and temperamental girlfriends further complicate his life. Andy Griffith stated in a Today Show interview, with respect to the time period of the show: "Well, though we never said it, and though it was shot in the '60s, it had a feeling of the '30s. It was when we were doing it, of a time gone by." The series never placed lower than seventh in the Nielsen ratings and ended its final season at number one. It has been ranked by TV Guide as the 9th-best show in American television history. Though neither Griffith nor the show won awards during its eight-season run, series co-stars Knotts and Bavier accumulated a combine
30 Rock

2006

30 Rock

2006
7.5
Liz Lemon, the head writer for a late-night TV variety show in New York, tries to juggle all the egos around her while chasing her own dream.
The Marvelous Mrs. Maisel

2017

The Marvelous Mrs. Maisel

2017
8.1
It’s 1958 Manhattan and Miriam “Midge” Maisel has everything she’s ever wanted - the perfect husband, kids, and Upper West Side apartment. But when her life suddenly takes a turn and Midge must start over, she discovers a previously unknown talent - one that will take her all the way from the comedy clubs of Greenwich Village to a spot on Johnny Carson’s couch.
Chuck

2007

Chuck

2007
7.7
When Buy More computer geek Chuck Bartowski unwittingly downloads a database of government information and deadly fighting skills into his head, he becomes the CIA's most vital secret. This sets Chuck on a path to become a full-fledged spy.
The Grand Tour

2016

The Grand Tour

2016
8
Jeremy Clarkson, Richard Hammond and James May are back with a show about adventure, excitement and friendship... as long as you accept that the people you call friends are also the ones you find extremely annoying. Sometimes it's even a show about cars. Follow them on their global adventure.
Heartbeat

1992

Heartbeat

1992
7.1
Set during the 1960s in the fictional North Yorkshire village of Aidensfield, this enduringly popular series interweaves crime and medical storylines.
Helluva Boss

2020

Helluva Boss

2020
7.9
In Hell, imp Blitzø (the 'o' is silent) runs an assassin business targeting the world of the living, using a spell book borrowed from a prince of the underworld. With employees Moxxie, Millie, and Loona, they attempt to survive each other while keeping business afloat.
Upload

2020

Upload

2020
7.8
In 2033, people who are near death can be “uploaded” into virtual reality hotels run by 6 tech firms. Cash-strapped Nora lives in Brooklyn and works customer service for the luxurious “Lakeview” digital afterlife. When L.A. party-boy/coder Nathan’s self-driving car crashes, his high-maintenance girlfriend uploads him permanently into Nora’s VR world.